PODCAST

In Conversation with

Mr Alastair Lamb

Mr. Alastair Lamb is currently an Honorary Consultant Urologist and Cancer Research UK Clinician Scientist at the Churchill Hospital in Oxford. In this episode he talks about his career and his work as an academic surgeon.

Mr Lamb completed his undergraduate studies at Oxford University in 2000 and then moved to Edinburgh University to complete his clinical studies. He then moved to Cambridge for an Academic Clinical Fellowship in urology, which subsequently led to his PhD. After further surgical and research training in Cambridge, he completed a GU oncology fellowship in Melbourne in 2016 and then moved to Oxford for his Consultant post.

Mr Lamb completed his undergraduate studies at Oxford University in 2000 and then moved to Edinburgh University to complete his clinical studies. He then moved to Cambridge for an Academic Clinical Fellowship in urology, which subsequently led to his PhD. After further surgical and research training in Cambridge, he completed a GU oncology fellowship in Melbourne in 2016 and then moved to Oxford for his Consultant post.

 

His clinical work focuses primarily on prostate cancer care for men in the Oxford regional area, focussing on multiparametric MRI and targeted transperineal biopsies, and the use of robotics to aid radical prostatectomy procedures. Other members of his team provide additional care with radiation or brachytherapy. HIs particular clinical interest involves broadening the scope of minimal access surgery including cytoreductive radical prostatectomy in locally advanced or metastatic disease. 

 

His research goal is to determine the molecular genomics behind prostate cancer in order to aid accurate decision-making early on in disease progression. His PhD thesis investigated the role of HES6 as a transcriptional driver in castrate resistant prostate cancer. He now leads a laboratory research group that employs integrative genomics in prostate cancer risk stratification with a particular focus on a new technique called “Spatial Transcriptomics” which combines single-cell next generation sequencing approaches with surgical histology.

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